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Showing posts with label Biotech Articles. Show all posts
Showing posts with label Biotech Articles. Show all posts

Friday, April 11, 2014

In-Vitro Meat: The Healthy Meat for the Future



Winston Churchill stated long back in 1932 that after fifty years, that man wouldn’t bother to grow a full chicken for meat and rather grow meat in a suitable medium. It’s more than fifty years now, but the wait won’t be long for in-vitro meat to reach the market. Things would speed up with PETA’s offering of $1 million to the first scientist who would release in-vitro meat in the market. PETA has been supporting the in-vitro meat research as there is a whole lot of harm being caused to animals and the environment to meet the meat addiction of people. Meat eaters are also concerned over the several diseases like heart diseases and diabetes that are increasingly affecting meat eaters. Contaminated meat has been reported to have caused several deaths in United States. Grazing has led to the insufficient utilization of croplands and has led to the depletion of resources. Excessive carbon di oxide, nitrogen, and other emissions into the environment have also led to concerns over the increased livestock and the need for in-vitro meat was recognized.
In-vitro meat has been devised as the best alternative to keep away from all the ill-effects of animal farming for meat. This is also known as cultured meat as meat is produced through tissue culture technique. In-vitro meat is not the same as the imitation meat for vegans which have been produced from vegetable proteins. The starting material for in-vitro meat is the stem cells derived from waste matter in slaughter houses. These stem cells are grown in a concoction of sugar, amino acids, lips and minerals. This has led to the growth of thin muscle like strips, the first precursors of in-vitro meat. Around 3000 of these strips has to be packed together and arranged with a few strips of lab-grown fat and the new product thus formed will be able to replace the conventional animal meat.
Due to the several steps involved in the production of in-vitro meat, the product is expected to be rather expensive when it reaches the market. The research are still going on and the first in-vitro meat will be grown with intensive care over looked upon by highly qualified academic staff in an academic laboratory. The process is partly handmade and requires enough of manual work done over in-vitro meat and therefore will be expensive. The scientists have also informed that the first productions will be a little awkward at sight as they will seem color due to lack of blood involved.
The issues faced by the world due to the increased demand for meat, was that what bought the attention of scientists to produce in-vitro meat. The destruction caused to the agricultural land and land wastage to feed the livestock is very high and will tend to increase ina tremendous rate in the coming years. This has been contributing in a great way to energy loss, land wastage, global warming, air pollution and decline of biodiversity. By replacing livestock meat with in-vitro meat, the damage that is being caused to the environment can be greatly reduced.
Mark Post is the man and the brain behind this artificial in-vitro meat production and plans to present the world the first man-made meat by August or September. He is a vascular biologist in the Netherlands University of Maastricht and is funded by an anonymous person. There are several people who have tested the in-vitro meat and have not been rather impressed with its taste when compared to livestock meat. Efforts are being made to add to the taste of this in-vitro meat by supplementing the lab-grown meat with the right amount and good quality artificial fat and a little of lab prepared blood rich in iron. Scientists believe that this can complement to the taste and look of the meat and soon can be made into tasty burgers and nuggets.

Wednesday, April 9, 2014

Greener Cities with Vertical Farming


Professor Dickson Despommier felt the need for alternative greenery and farming in the cities and he came up with the term Vertical farming which made use of aeroponics and hydroponics to grow plants without soil in the city buildings named as ‘farmscrapers’. We have only limited land and water supply and there is high demand for space and water. According to the reports, by the year 2050, there would be no land unoccupied by man where cultivation and farming could be done. There is a rampant search to find a good alternative to produce feed without using up much space. This was then that Dr. Dickson Despommier came up with the thought of Vertical farming.
We depend upon land to live, like farmlands to grow crops and animals and we also need the forests to keep the atmosphere fresh and oxygen filled. With people being worried over the consequences of excess land usage and the issues related, the idea of Vertical farming has been very warmly welcome by the masses. The idea of growing and farming plants, cattle, fishes and poultry in concrete and glass buildings in the heart of the city, under controlled environment is on its way to becoming a reality. The benefits that Vertical farming provide makes it preferable than conventional farming.
With vertical farming, crop production will become more efficient and healthy. They are grown in a controlled environment and therefore there is no way that insects or pests can enter the ‘farm’. The food thus obtained from vertical farming will be of better quality and contamination free as there are no pesticides or insecticides used in vertical farming. The crops can be grown in purely organic cultures and thus the quality of the crops thus produced can be ensured. The loss of crop and farm lands due to natural disasters and changing climates is prevented with vertical farming. The temperature is maintained at the optimal level and also, any fruit or vegetable can be grown according to the demand in that area as there will be no seasonal restrictions in vertical farming.
 Vertical farming ‘farmscrapers’ are intended to located within the cities and this will contribute in a huge extent to the transportation charges and the related fuel emissions while transporting it from distant villages. In these vertical farming centres, the black water will be recycled and reused for irrigation and this will help to reduce the scarcity for drinking water which is one of the major problems that the world is facing today. When compared to conventional farming methods, the bulk load of water that is spent in cultivating a crop is several times more the water that is used in vertical farming. Reuse and recycling of water will be done in the maximum possible ways within these vertical farming towers. Even the transpiration waters are collected are used in the controlled environment. This will also reduce the events of contaminated water run-away from the farmlands into the lakes and rivers.
Vertical farming is not a benefits alone technology and has its related disadvantages too. One of the main problems of vertical farming is absence of pollination. Under controlled environment, there will be no insects that bring about pollination and thus pollination will have to be manually performed. Due to the involvement of intensive labour, the crops, fruits and vegetables produced from vertical farming will be priced high. The whole set-up of these vertical farming towers will involve a good deal of investment as land, creation of the vertical farming lab, lights, temperature and ambience settings and other related expenses. There are several limitations and scientists are working to make vertical farming a reality.

Sunday, April 6, 2014

Vitrification, Preservation and Cryoprotectants




We all know that living organisms are primarily composed of water and on freezing, these water molecules convert into ice. There are many amphibians and insects who can withstand freezing without converting into ice. Amphibians like frog produce glycerol by the liver and it works like ‘antifreeze’. Glycerol, ethylene glycol etc. are cryoprotectants and prevent ice formation. The cryoprotectant prevents water from forming into crystals and makes it harden like glass. This is known as Vitrification. At freezing temperature, normal cells get damaged due to ice crystal formation. When a cryoprotectant is used the water molecules get frozen in their own locations without forming the ice crystal lattice. This thus causes no damage to the cell and thus the cells, tissues and even whole organs can be maintained in that particular biological stage without causing any damage to it.
Cryoprotectants work by reducing ice formation, but there are substances which are known by the name of ice blockers which are targeted towards ice nuclei formation and thus stop freezing. This was first observed in artic fish which used certain anti-freeze proteins to prevent freezing. To bring about Vitrification, cryoprotectantshave to be used in very high concentrations which might at times lead to toxicity. The problem was that cryoprotectants became too viscous at high concentrations making perfusion difficult. This problem was effectively solved by using ice-blocker along with cryoprotectant to bring about optimal vitrification.
Glycerol was the first ever cryoprotectant used initially to freeze store bull sperm and was later adopted to store red blood cells. Later DiMethyl Sulfoxide was used for vitrification where it was used along with glycerol and slow cooling technique to store mouse embryos which were later rewarmed to produce live mice. The breakthrough in vitrification storage was when the 8 cell human embryo was preserved at liquid nitrogen temperature by using the optimal concentrations of DMSO at the several stages. Human embryos are now preserved at 4 and even 2 celled stages using a combination of DMSO, glycerol and propylene glycol. Today, over a million embryos are being preserved worldwide and have been proven to be a giant leap towards infertility treatment. There are several children round the world who have been once cryoprotected embryos at liquid nitrogen temperature.
Glycerol was used effectively for cryopreservation of human blood and sperm and was also used to prevent freeing in cryonics patients. The problem was due to the viscosity of glycerol in high concentrations that it could not bring about complete vitrification. The problem was well realized when the need came up to vitrify tissues and organs. Glycerol as cryoprotectant could only bring about partial vitrification with 20% ice formation. Some organs can become completely damaged even by small ice crystals as it affects the connection between the cells. Crystallization when using glycerol for vitrification can be prevented by using glycerol solution of the optimal concentration of 68%volume/volume glycerol and water solution. At this concentration there was no crystallization that occurred and water hardened like glass.
The devitrification problem is caused mainly due to the rewarming of a cryoprotected tissue which leads to ice crystal formation. This can cause damage to the tissues, organs or cells on re-obtaining the cells from its vitrified stage. This devitrification problem can be prevented by rewarming at high temperatures quickly. According to reports, researches and calculations, to bring about rewarming without devitrification problem, it is required to deliver 1667 degree temperature in a sec. This high and quick temperature to retrieve vitrified cells can be obtained through radio frequency rewarming. Anti-nucleators like polyvinyl alcohol can also bring about rewarming without causing destruction to the cells.

Friday, April 4, 2014

Biosomatic Cellular Engineering


Stem cells have been in the limelight since the time its potential was discovered and there are several stem cell researches going on round the world including biosomatic cellular engineering. Stem cells have been recognized to be used to heal wounds, repair aging, replace organs, overcoming traumatic injuries and even can be said to stop death as a whole through biosomatic cellular engineering. It could be used positively to lengthen and strengthen life. Stem cells are unspecialized cells which can reproduce unendingly for a long period of time. They can be triggered at any point of their growth to become specialized cells like tissues or even organs. 
Biosomatic cellular engineering has come as a new division of science which aims to prolong the life of tissue by using young stem cells.

Aging is one of the most prominent human processes and Biosomatic cellular engineering aims that aging and looks unto human stem cells to act against aging and retain the youthfulness of the organism. There are basically three kinds of stem cells, the embryonic stem cell, embryonic germ cell and adult stem cell. To date, it has been the embryonic stem cells which are widely used in researches aimed at disease cure and aging as they are pluripotent. Adult stem cells are not pluripotent and can only generate certain cell types according to their genetic coding. Even isolating and replicating them in a laboratory conditions is a difficult task, making adult stem cell the least desirable for research purposes.
Biosomatic cellular engineering is a branch of science that devices newer techniques and ways by which the adult stem cells can be produced in lab conditions. The adult stem cell thus produced via biosomatic cellular engineering should be able to have all the properties like embryonic stem cells and does not induce cancer through biosomatic cellular engineering. This aims at producing a universal bank for adult stem cell that does not contain any kind of antigen. In the absence of antigen, the body will not reject the stem cells during transplantation. Later, for the stem cell to be accepted by the recipient, back HLA and other specific antigens can be used. This is a simple hypothesis for making it possible that adult stem cells can fight aging supporting the cause of biosomatic cellular engineering. There are several researches being carried out in biosomatic cellular engineering, in collaboration with organ printing, nanotechnology and synthetic biology to make this thesis a reality.
There are several restrictions and limitations for the usage of embryonic stem cells. There have been several reported cases where foetal stem cell transplantation lead to cancer in the patient. Foetal stem cells were found to have high potential in treating several diseases and yet scientists had raised concern over using the technique as there remained possibilities that stem cells injected into an organism could replicate and lead to tumour formation. With biosomatic cellular engineering, this chance of tumour formation could be avoided as adult stem cells do not proliferate quickly like foetal stem cells. Studies are being conducted in biosomatic cellular engineering, where adult stem cells are being used to treat stroke by injecting adult stem cells into the brain. They go to their specific site and bring about tissue repair and once the job is done, they die off rather than proliferate.
Muscle deterioration is one of the signs of aging and with biosomatic cellular engineering, muscle adult stem cells when injected into the organism can make the muscle strong and thus halt the aging of the muscles. The muscle stem cells carry out muscle repair function and on reinjection, they perform the same job when experiments were conducted on mice. The same when applied to every aspect of aging can be very useful in preventing the whole process of aging through biosomatic cellular engineering. 

Wednesday, April 2, 2014

What is Biotechnology?


Recent advances in biotechnology are helping us prepare for and meet society’s most pressing challenges.

 At its simplest, biotechnology is technology based on biology - biotechnology harnesses cellular and biomolecular processes to develop technologies and products that help improve our lives and the health of our planet. We have used the biological processes of microorganisms for more than 6,000 years to make useful food products, such as bread and cheese, and to preserve dairy products.
Modern biotechnology provides breakthrough products and technologies to combat debilitating and rare diseases, reduce our environmental footprint, feed the hungry, use less and cleaner energy, and have safer, cleaner and more efficient industrial manufacturing processes.

Currently, there are more than 250 biotechnology health care products and vaccines available to patients, many for previously untreatable diseases. More than 13.3 million farmers around the world use agricultural biotechnology to increase yields, prevent damage from insects and pests and reduce farming's impact on the environment. And more than 50 biorefineries are being built across North America to test and refine technologies to produce biofuels and chemicals from renewable biomass, which can help reduce greenhouse gas emissions.
Recent advances in biotechnology are helping us prepare for and meet society’s most pressing challenges. Here's how:


Heal the World


Biotech is helping to heal the world by harnessing nature's own toolbox and using our own genetic makeup to heal and guide lines of research by:
·         Reducing rates of infectious disease;
·         Saving millions of children's lives;
·         Changing the odds of serious, life-threatening conditions affecting millions around the world;
·         Tailoring treatments to individuals to minimize health risks and side effects;
·         Creating more precise tools for disease detection; and
·         Combating serious illnesses and everyday threats confronting the developing world.

Fuel the World

Biotech uses biological processes such as fermentation and harnesses biocatalysts such as enzymes, yeast, and other microbes to become microscopic manufacturing plants. Biotech is helping to fuel the world by:

·         Streamlining the steps in chemical manufacturing processes by 80% or more;
·         Lowering the temperature for cleaning clothes and potentially saving $4.1 billion annually;
·         Improving manufacturing process efficiency to save 50% or more on operating costs;
·         Reducing use of and reliance on petrochemicals;
·         Using biofuels to cut greenhouse gas emissions by 52% or more;
·         Decreasing water usage and waste generation; and
·         Tapping into the full potential of traditional biomass waste products.


Feed the World


Biotech improves crop insect resistance, enhances crop herbicide tolerance and facilitates the use of more environmentally sustainable farming practices. Biotech is helping to feed the world by:
·         Generating higher crop yields with fewer inputs;
·         Lowering volumes of agricultural chemicals required by crops-limiting the run-off of these products into the environment;
·         Using biotech crops that need fewer applications of pesticides and that allow farmers to reduce tilling farmland;
·         Developing crops with enhanced nutrition profiles that solve vitamin and nutrient deficiencies;
·         Producing foods free of allergens and toxins such as mycotoxin; and
·         Improving food and crop oil content to help improve cardiovascular health.

Sunday, March 30, 2014

Overview of Biochemistry


Biotechnology has become an important scenario now-a-days in this modern world.

Biotechnology as the name suggests includes technology related to living organisms which also specify about genes, chemical reactions, chromosomes, enzymes etc and various other parameters associated with it.

Of all, let us now enlighten with some facts about biochemistry. Biochemistry deals with the chemical changes that occur in living organisms. The reactions may be outside the cell (extracellular) or inside (intracellular).

Reactions involving bond breakage like hydrolytic reactions fall under extracellular reactions and reactions such as oxidative reactions come under intracellular reactions.

Basically biochemical reactions either extracellular or intracellular are temperature dependant. Biochemical reactions in general occur at temperatures between 0°C and 60°C. Depending upon the range of temperature, the organisms have been classified as Cryophilic, Mesophilic and Thermophilic.

Cryophilic organisms thrive at cold temperatures, Mesophilic at room temperature and Thermophilic at high temperatures. At sometimes in order to boost up a reaction certain additional materials are required and they are termed as catalysts. A catalyst typically speeds up the reaction to obtain the final product with out disturbing the existing reaction scenario. These catalysts may be supplied by the living organisms themselves as a part of their life/metabolic processes and they are termed as Enzymes.

Again these enzymes depending on their secretion from outside the cell or inside the cell can be classified as extracellular enzymes and intracellular enzymes respectively. Enzymes are generally proteinaceous by nature.

These enzymes thus play a vital role in maintaining metabolism and the study of these help mankind to take a step forward in the field of biotechnology.

Friday, March 28, 2014

Lampbrush Chromosomes


Chromosomes can be found in nucleus which can be found in every cell where it can absorb dyes. The term is more commonly associated with being visible during cell division. A human being has forty six chromosomes where a potato has forty eight chromosomes. When chromosomes are seperated each daughter will receive a number of chromosomes and the factors are able to determine the characteristics of all living creatures and this is where the Special Chromosomes: Lampbrush Chromosomes come into play a very important part of the make up.

A chromosome is a thread like part of a cell which carries relevant information to form genes. There are two different chromosomes which are known as eukaryotic or prokaryotic. Humans are known to have twenty three pairs of these and they consist mainly of DNA.


Throughout the cell cycle chromosome's can actually change although they are very long they are also thin. During cell division they appear shorter and thicker which can be observed under the microscope.

These are distinguished from one another by their actual length and position The centomere actually lies between two chromosome arms which hold the genes as well as other DNA sequences which do not have any known functions.


In every nucleur cell in either a human or an animal it actually contains six pairs of DNA which if this was to be spread out it would measure around six feet long. Each diploid organism has a character number of Lampbrush Chromosomes which can amount to hundreds in butterflies.


In birds and some other forms of reptiles there are around thirty of forty of microchromosomes which are very small, compaired to around five or seven pairs of the regular size.


In many species of insect, plants and other creatures the number of chromosome's can literally differ because of the main presence of accessory chromosomes that can be found which are known as B chromosomes it is not actually clear what role these actually play.


In most of the mammals the sex of the individual can actually be determined by whether or not the Y chromosome is present because of the Y chromosomes carries the male SRY gene. And the more uncommon XXY individuals are actually male. It has been reported than more than nine hundred gene loci have been associated with the human X chromosome.


It was back in 1888 that  Lampbrush Chromosomes and their descriptions were made by the German geneticist W. Von Waldeyer-Hartz who had described them as actual solid bodies, that are able to stain strongly by the use of dyes.


The changes of the actual appearence of these Lampbrush Chromosomes which is due to cellular life cycles which are actually caused the chromosomes functional characters and much of these types have been served as the basis of chromosome's theory of heredity.


Chromosome's are attached to the cytoplasm membrane in many different places, mainly this is by way of telomeres and also centromeres. Each chromosome has the facility to create its own copy of replication of DNA.

Wednesday, March 26, 2014

Protein Sorting


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Protein Sorting is the process of how protein is transported by a cell to the right positions either inside or outside of it. The actual delivery process is carried out on the actual information which is found in the protein itself.

The reason for the correct sorting of these proteins is crucial for being able to find errors that could lead to such diseases. The repeated stretch of the amino acid and it was back in 1970 when Gunter Blobel conducted some research into the transition of proteins and he was actually awarded the Nobel Prize in 1999 for his efforts.


Although the majority of the proteins are actually translocated some can be found in the cytosol and only later reach their destination. This also occurs for proteins for being able to carry out Protein Sorting.

They are actually capable of passing through the nuclear envelope via the pores themselves. And the amino acid actually passes through the membrane several times and this happens by the use of translation.

These such membrane proteins are mostly understood by using a process known as Protein Sorting. However many of the proteins do actually contain many structural aspects that unfortunately do not relatively fit the model.


The majority of proteins are therefore needed for both mitochondria and also chloroplasts as well where the characters are divided into two specific ones that are indeed needed for this very important process.


Defective proteins can be occassionally produced and can actually be found in eukaryotes but can attach themselves to other various types which includes gas vesicles and also bacteria can actually have plasma membrane which can be secreted into the actual environment itself.


Therefore in addition to this the protein can in actual fact be quite a complexed procedure although it does indeed play a very important part in many pathogenisis. And these can therefore be described as either type one secretion or type II secretion.


The final conclusion of being able to carry out such Protein Sorting is where you are able to direct a polypepitide to a certain direction and this is what is known as targetting your protein. And this is a very important function that is carried out regularly for being able to function the eukaryotes cells.


This actual method occurs on many several levels of existence which has actually been encoded by the use of DNA which has been found in mitochondria  and also chloroplasts as well.


The very first Protein Sorting hapens at growth as these have specific targets that is able to direct the ribosomes and then take them towards the ER protein that then completes on the ribosomes All synthesis of these nuclear proteins is then completed.


Although many of these such proteins are then sorted to be able to reach their correct destinations and each sorting event therefore has the involvement of signal sequence which is either found on the surface or interior of the organelle.


Then such proteins are then placed into cells following the Protein Sorting to the specific cell surface receptors.

Monday, March 24, 2014

Nerve Cells And It's Excitation


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A Nerve Cells And It's Excitation is a cell that can transmit information by using electrical and chemical signalling. These such neurons are able to connect each other to being able to perform a network.


These neurons are therefore able to make up the nervous system which includes the brain and the spinal column and also can affect such things as glands. These therefore possess a cell body and these are quite often extended to hundreds of micrometres and it is also where the cell body in a neuron quite often gives out frequent rise to many multiple places, but never to actually one than more axon.


When you take a look at neurons of an adult brain and take a look at these Nerve Cells And It's Excitation you will see how they actually undergo cell division and once they have been lost they cannot be replaced.


Although like anything else there are a few exceptions to the rule and where they have been generated by stem cells. A typical neuron is actually divided into different parts which are the soma, dendrites and also the axon.


The dentrites generally though branch out getting a lot thinner with each and every branching that they carry out from a few hundred micrometres from the soma itself. Whereas the axon has the capability of extending for a great many distances for Nerve Cells And It's Excitation.

Neurons have been known for highly specializing in processing the transmission of cellular signals. And taking a look at the many functions that the neurons can perform in different areas of the nervous system. Where the soma can develop from around four to hundred micrometres in diametre.


Much of the protein synthesis occurs in the nucleus of the actual cells itself. These such neurons can present themselves in different sizes and shapes and can be pinpointed out by their morphology and the functions that they carry out.


It was in the year of 1937 that John Zachary Young brought up the idea that the giant axon could actually be used for resarch purposes for studying electrical properties which were a lot larger than the human neurons. Some of these neurons that are found in cells do not actually generate potentials with the Nerve Cells And It's Excitation.

When we find ourselves coming across information that is found in the brain it is known as neural coding. The main issue is the character of the actual relationship found in the stimulus and the neuronal responses.


The actual word neuron came from the German anatomist Heinrick Wilhelm Waldeyer. And the function of the nervous sytem was not associated until the 20th century through the work of Santiago Ramon y Cajal. And he showed us how the neuron cells could discrete the cells that were able to communicate with each otherby way of different junctions between the actual cells themselves.


The actual doctrine of the such Nerve Cells And It's Excitation are the actual basic structural of the function units of the nervous system, and the number of neurons found in the brain differs from species to species. One of the estimates has put the human brain in about a hundred billion neurons.



Friday, March 21, 2014

ATP Dependent Proton Pump


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The use of guinea pig brains has been associated with ATP Dependent Proton Pump and it is where they operate a quick freeze technique which shows a 'knob-like' appearance on the surface.


This is necessary for being able to package neutrotransmitter into synapic vesicles. These play a very essential role as the transmitter for being able to store and release compartments for the nerve terminals. It has been suggested that a ATP Dependent Proton Pump creates an electro chemical across the vesicle membrane.


There are many different varieties of intracellular membrane bound organelles. Many of these are associated with ATP Dependent Proton Pump and that many of the brain might actually contain very similar pumps.


These have been further characterized and the ATP Dependent Proton Pump has been successfully applied where others have been isolated. These have been investigated and looked at thoroughly where activity has been through a technique where methylamine distribution was used in very similar circumstances to the clathrin coated vesicles.


The great possibility of being able to look at contamination with these smooth vesicles. This is why the purified coated vesicles from the right amount of genuine pig brains is commonly being used for being able to show ATP Dependent Proton Pump and how the protein basis that has been observed can actually can account for around ten to twenty per cent of the synaptic vesicle.


The addition of this type of procedure used to be able to isolate these types of vesicles and has therefore been designed to be able to give optimal yield of these such smooth vesicles where they have the power of contaminating the final vesicles.


Therefore it has been suggested that the use of the proton pump activity has been closely observed in a fraction is not actually connected to contaimination. It has actually been suggested that these protrusions that have been found on the surface of the chromaffin granules might actually be a ATP Dependent Proton Pump.

It was therefore necessary to rule out these such contaminations of the vesicle preparations and this when then introduced by issuing Sephacryl S 1000 in this such purification process. This was actually quite small only measuring around forty to fifty nm in size although these needed to understand their actual functions.


This therefore shows that these such results and actually confirm earlier reports that these less purification processes that were suggested back in 1979 that there was an increase of ATP activity and that the transmitter content was not indeed parralel.


This therefore has the power to reflect the actual loss of the transmitter during this such preparation process. And that the activity of the ATP Dependent Proton Pump which has been compared and demonstrated these types of synpatic versicles from guinea pig brain and has the power of showing the main three features.


Which therefore has the ability of being able to cut off from the actual membrane and that the ATP Dependent Proton Pump which shows on the surface of the particle. And it is a great possibility that these such 'knob like' protrusions are indeed the equivalents of ATP enzymes.

Wednesday, March 19, 2014

Programmed Cell Death


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Programmed Cell Death is where cells literally destroy themselves and this is actually controlled by nuclear genes.The DNA firstly would break into tiny segments and then the nucleus would finally break down which then results in the cell shrinking and then breaking up, this then plays an important part of being able to maintain the healthy life of organisms.


There are two types of cells death which are commonly known as Cell I and Cell II. A Apoptosis is a cell I death and a Autophagic is a cell II death. Cells that are found in plants undergo processes of cell death although some of the common factors of cell death are conserved in plants.


There are indeed many factors that actually would cause a cell to die and these include a decreased workload, low nutrition, sensitivity and also increase in blood supply are just some of these known factors for resulting in Programmed Cell Death.

This was first brought about back in 1964 by Lockshin and Williams and this has become very popular for research interventions. This has been optimized with the award back in 2002 for being awarded the Nobel Prize for Medicine. In this procedure instead of having an immune system to back it up it has substances that helps to break itself down and then puts it into a vacuole which then tears when the cells die.

In plants especially the stalk of the plant has many dead cells which have actually gone through the process of Programmed Cell Death although there is no appearance of DNA fragmentation the main aim of the residues that have been left behind from the dead cells has no PCD in these plant tissues.


Many of the biologists therefore believe that mitochondria which has come from bacteria which therefore brought together endosymbionts and it was therefore in 1967  that Lynn Marqulis. Many cells are able to respond to different specific molecules and without this then would go through cell death.


You may ask why do these actual cells die? Well there are numerous answers to this question but relatively speaking the majority of them die because of either trauma or they starve to death. Some cells that actually develop an infection of some sort frequently develope Programmed Cell Death.

This then has the power of taking away cells which then omits the spreading of the virus infection Frogs are a good example of this where a tadpole is able to further develop into a fully grown frog.


All living things live off of light and this then travels in forms of lengths and this is shown in the same procedure when we talk about Programmed Cell Death by removing cells that have been damaged we are eliminating the disease to spread further and cause virus infections by removing the source of infection in the first place.


The talk of cell death has been around for many, many years although much of the functions are relatively the same the technology and study has changed dramatically over the years.